virus types coronavirus arenavirus (arena - have sand) lassa filovirus (have filaments) ebola marburg flavivurus etiology - cause of the disease pathogenesis - biological mechanism that leads to the disease signs - observed by doctor symptoms - described by the patient DNA virus - carries own (usualy double stranded) DNA: smallpox RNA virus - causes direct protein construction from viral RNA: cold, flu, SARS, COVID-19, West Nile, Ebola, polio, measles retrovirus - carries RNA, but insde the cell causes to produce DNA then start building viral proteins: HIV attack rate = number of new cases (per time inteval) in the population at risk/ nmber of people at risk on the population virulence - ability to infect or damage the host assay - procedure of measuing the amount or functional activity of the target entity (the anlyte) vector - agent which caries and tranmits the pathogen into another oranism index case (patient zero) - first documented patient in an epidemic, may not necessarily be the source reservoir - a living host of certain species inside which a pathogen survives often (but not always) causing the disease in the reservoir cox postulate DISEASES Smallpox - variola virus 30% death rate variolation - inserting powdered smallpox scabs or fluid to scratches on skin 1-2% death rate vaccination - use (mild) cowpox virus to innoculate Yellow Fever Measles Poliomyelitis - enterovirus (goes through the gut) Lassa Fever Ebola Hantavirus SARS West Nile Mad Cow the Flu AIDS